Thanks DrKK! That was exactly what I wanted to know. Think I'll go with RAID-Z2.
You also brought up another point... Usually, I use 'enterprise' drives (Not the SAS ones with small capacities, but the better quality SATA drives), and stay away from Seagate. I know this changes every few years (I used to do Data Recovery). I've been happy with Hitachi, and have also had good results with Fujitsu. So WD Reds are the way to go nowadays? Any other recommendations?
RAID-Z2 on four drives is considered "butt-clenching/extremely hard core". 50% redundancy on a 4-drive pool is a very conservative position, to say the least.
As for hard drive makes and models, obviously, these topics have the hazard of leading to jihad in any room where large numbers of smart people are gathered. So let me tell you where, generally as a community, we are with these things. I would say almost all of us would agree with the following broad statements:
* Everyone thinks WD reds (non-'Pro' version) are very good. Cyberjock runs them, exclusively. I run them, exclusively. Every single FreeNAS I have ever built for someone uses them, exclusively. ixSystems chooses them to populate their FreeNAS Mini, exclusively, and has since the beginning of that product. Problems are rare (I, for example, have never had a single bit out of place on my NAS, nor have any bits every been out of place on any NAS I've built), and WD has made it a point to have smooth RMA pipeline for their NAS drives.
* All sizes of the WD red have shown themselves to be reliable; even the 6TB has shown itself anecdotally by our guys here and then again over at Backblaze, to be good drives.
* We do not recommend the WD "pro" reds. They are much more expensive to an extent that we believe do not justifies the additional cost, there is no evidence that they are better, and they are higher energy consumption/RPM. The higher energy cost, and much higher cost of the drives, does not offset the slightly longer warranty nor the marginal performance improvement theoretically possible with the higher RPM.
* 9 out of 10 of us with an opinion on Seagate have a "no ****ing way" policy on Seagate. We see lost pool after lost pool after lost pool, and SMART after SMART after SMART, and our experience is just that Seagate is not at the same level of reliability.
* The research from people that we don't think are stupid (that's always the trick---you have to modulate out for people that are believed to be stupid) would seem to indicate that the HGST NAS drives are probably outstanding, and even though very few of the most active guys on the forum are using them (most of us are using WD reds), I think we all accept at this point that the HGST NAS drives are at least the equals of WD Red in terms of quality, and may be the best drives on the market.
* I don't suggest, and I don't believe most of the guys would suggest, that you spend the money for "pro" or "SATA enterprise" drives. We generally think that's money down the drain since the regular grade HGST NAS and WD reds are just about as good as it gets anyway.