4 vdevs of 6 drives in z2? This is also 16 drive capacity. Instead of the 'warm spares' of the double z3, this 'integrates' the spares into the pool. Also 'optimal' number of drives per vdev if you subscribe to that sort of thing. Likely to be faster as well. This is 33% parity.
It integrates the spares into the pool, yes. It also means that a triple drive failure can dump your entire pool, though you have to suffer some seriously bad luck in order to land all three failed drives in a single vdev.
From my perspective, this is less desirable because we'll be pulling the drive for RMA. With 2x11+2, an array temporarily becomes 2x11+1 while that failed drive is out for several weeks, and indeed can even suffer another failure/rebuild-on-spare event, all while continuing to run at full non-degraded mode (except during the rebuild of course).
When a 4x6 fails a drive, you either need a cold spare standing by, or you need to suffer reduced redundancy (and the performance hit of degraded mode) while the drive is out for RMA; if you lose a second drive, you have an approx. 1-in-4 chance of actually losing redundancy entirely.
From an operational perspective (not relevant to home users I know), not having to dispatch someone to replace a drive at 3AM is a very attractive thing. With the two warm spares, it means that a remote administrator can virtually swap in a disk twice without anyone being on site, so if you think about it like that, it is kind of like RAIDZ4 with the ability to suffer a disk failure and not stay degraded pending a physical disk swap.
I am not convinced that what is probably a mild performance gain offsets that, but I enjoy the debate so don't hesitate to tell me I'm full of it (just tell me why!).
Another option for more capacity, but less redundancy:
3 vdevs of 8 drives in z2. This is 18 drive capacity. 'non optimal' number of drives per vdev, but for media storage, this is unlikely to matter. This is 25% parity. With a cold spare or two kept in a drawer, I'd probably consider this.
I agree that the speed issue is unlikely to be a problem for media storage, but then again, in this era, even a fairly small slow server ought to be able to serve up media without being too stressed. Once you're talking more than six or eight disks, the server ought to be sufficiently large and there ought to be sufficient IOPS to handle media retrieval.
If absolute storage is the overriding concern, I'd say push out to 12-drive vdevs at RAIDZ3. There's anecdotal evidence of people having success with vdevs up to 18 or even 24 drives, but it is also pretty easy to find
reports of failures, and trying to find a way to back up a 24-disk pool so you can blast it and reload it would ... be annoying to the average user. But since your average storage chassis will be in a 12, 24, or 36 disk version, 12 is really a compelling number of disks to be working with.